Aspirin may benefit cancer treatment

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A new meta-analysis finds that aspirin is a cheap and easily available drug that may benefit cancer treatment, prevent the spread of metastatic cancer and reduce vascular complications.

The Wells Aspirin Group at Cardiff University has published a systematic review and meta-analysis examining the impact of using aspirin to treat cancer.The study, titled “Aspirin and cancer treatment: a systematic review and meta-analysis of the evidence: for and against,” was published in British Journal of Cancer.

The study examined the results of 118 observational studies based on about 1 million patients with various cancers and found that taking low-dose (75 or 81 mg/day) aspirin daily was associated with a 20% reduction in cancer deaths. % related. Cancer and death from all causes.

“Aspirin was first shown to be beneficial in the treatment of cancer in 1968 because it targets many of the key biological mechanisms of cancer, reducing the risk of metastatic cancer spread and vascular complications in cancer patients. Our experience with aspirin in the treatment of cancer Research review “The treatment finds positive evidence supporting its use in cancer treatment. The use of low-dose aspirin in cancer treatment has been shown to reduce the spread of metastatic cancer and reduce complications related to blood clots.” Cardiff University.

Aspirin is known to increase the risk of gastrointestinal bleeding. The study aimed to assess the risks of using aspirin in cancer treatment, including risks associated with gastrointestinal bleeding. The report from the Wells Aspirin Panel, which reviewed studies of aspirin-related gastric bleeding, found that gastric bleeding caused by aspirin was less severe than gastrointestinal bleeding in patients with gastric ulcers or stomach infections. And there is no valid evidence that aspirin causes fatal bleeding.

The researchers concluded that given aspirin’s relative safety, it should be promoted as a cancer treatment because there is consistent evidence that aspirin can reduce metastatic cancer spread and reduce the risk of metastatic cancer after a cancer diagnosis. The sooner you start taking aspirin, the better it will be. Benefit from aspirin.

“We believe that given aspirin’s relative safety and its beneficial effects, its use as an additional treatment for cancer is fully justified.

Professor Elwood added: “Because aspirin is cheap and readily available in almost every country, its rollout could bring benefits worldwide, and because of current delays in specialist services for patients with suspected cancer, This reduction could have huge benefits.”

More information:
Peter Elwood et al., Aspirin and cancer treatment: a systematic review and meta-analysis of the evidence: for and against, British Journal of Cancer (2023). DOI: 10.1038/s41416-023-02506-5

Provided by Cardiff University

citation: Aspirin may benefit cancer treatments (2023, December 4), Retrieved December 11, 2023, from https://medicalxpress.com/news/2023-12-aspirin-benefit-cancer-treatments. html

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