Green tea or pumpkin essential oil reduces brain damage in rats with multiple sclerosis

A new study reports that treatment with green tea or pumpkin essential oil reduces brain damage in a rat model of multiple sclerosis (MS).

These oils also help restore abnormal levels of neurotransmitters chemical messengers that nerve cells use to communicate, and reduce inflammation, cell death, and markers of a type of cell damage called oxidative stress.

In particular, pumpkin essential oil is thought to have certain benefits for these animals, and the findings “are consistent with previous research demonstrating the potent antioxidant properties of pumpkin essential oil.” [green tea oil]”.

“Our findings show [pumpkin oil] Neuroprotective effects may be related to high concentrations of antioxidant compounds… which may help prevent inflammation and chronic disease,” the researchers wrote.

Research,”Ameliorative effects of green tea and pumpkin oil on myelin oligodendrocyte glycoprotein-induced multiple sclerosis in rats,”published inFunctional Food Magazine.

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Need to study the effects of pumpkin and green tea essential oils on the human body

Essential oils are oils that contain the main bioactive compounds found in specific plants. The term “essential oil” can be a bit misleading, as these oils are not essential for human health. Instead, the term refers to oils that contain essences and therefore the essence of the plant.

Many different essential oils have been used in traditional medical practices for a long time, and in recent years, scientists have begun using modern scientific methods to test their potential value in healthcare applications.

Here, an international team led by Egyptian scientists tested the effects of two essential oils (green tea oil and pumpkin oil) in animal models of multiple sclerosis. Researchers note that both essential oils are reported to have anti-inflammatory and antioxidant properties.

Multiple sclerosis is caused by inflammatory attacks in the brain and spinal cord that damage myelin, the fatty protective layer around nerve fibers that helps them send electrical signals. In their experiments, the researchers used a rat model in which the animals were essentially vaccinated to trigger an autoimmune attack against proteins in the myelin sheath.

When the first disease symptoms became apparent, some rats were given an inactive vehicle solution as a control, while others received green tea or pumpkin oil orally every day for three weeks.

Analysis of the rat brains showed that rats in the control group had extensive brain tissue damage, but rats treated with both essential oils had significantly less brain tissue damage.

These compounds may help treat multiple sclerosis.

In control rats, induction of multiple sclerosis-like disease resulted in significant decreases in levels of neurotransmitters, including dopamine, serotonin, norepinephrine, and acetylcholine. Rats given either essential oil had significantly higher levels of these neurotransmitters compared to control rats.

Another neurotransmitter called epinephrine was significantly increased in the sick mice given the control solution, but these levels also returned to normal after using either essential oil.

The treatments also resulted in reduced markers of inflammation in the brain compared with controls. Essential oil treatment also reduced markers of oxidative stress (a type of cell damage caused by inflammation) and apoptosis (a type of cell death) compared to untreated control rats.

Overall, the researchers concluded that green tea oil and pumpkin oil “suppressed neuronal degeneration, oxidative stress, inflammation, and apoptosis in the cerebral cortical tissue of diseased rats.”

“Thus, these compounds may be useful in the treatment of multiple sclerosis,” the researchers wrote. They called for further research to test the potential therapeutic value of these two essential oils in humans.

In this study, researchers used essential oils marketed by the Egyptian company Nefertari. The company was not directly involved in the research, which was funded by King Saud University.

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Image Source : multiplesclerosisnewstoday.com

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